Wednesday Slide Conference 2010 - 2011 Conference 21 23 February 2011
نویسنده
چکیده
Histopathologic Description: Cervical spinal cord: Microscopically, the lesions are characterized by a loss of myelin visible on HE-stained sections where the normally intense eosinophilia of the white matter is lost and the neuropil to has a fine fibrillar meshwork pattern dotted with numerous oligodendrocyte nuclei. With the Luxol fast blue stain, the deep blue color of the white matter is replaced by a light blue staining. A narrow rim of normal white matters is usually present between the edge of the lesion and the glial limitans, a characteristic sharp line of demarcation between the normal white matter and the lesion. The demyelination is associated with edema, swelling and splitting of myelin sheaths with gitter cells and a marked reactive astrocytosis. Only mild axonal changes (Wallerian degeneration) are seen, attesting axonal preservation. The vessels permeating the lesion are prominent and cuffed by mononuclear phagocytes.
منابع مشابه
Department of Veterinary Pathology WEDNESDAY SLIDE CONFERENCE 2001 - 2002 CONFERENCE 6 17 October 2001 Conference Moderator
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Wednesday Slide Conference 2009 - 2010 Conference 22 28 April 2010 Conference Moderator :
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